ABSTRACT
Eighty percent of hepatocarcinomas are inoperable at the moment of diagnosis. Liver transplantation is the treatment of choice in these cases, but local therapies are another alternative. Among these, Image-Guided BrachyAblation is a safe choice. We report a 76-year-old male with a hepatocarcinoma, who was considered inoperable due to the high surgical risk of the patient. A local treatment with Image-Guided BrachyAblation was decided. A brachytherapy needle was placed in the tumor under computed tomography guidance and a 15 Gy single dose was delivered from an Iridium-192 source. The patient had no immediate complications and at one month of follow up he continued without incidents.
Subject(s)
Humans , Male , Aged , Brachytherapy/methods , Carcinoma, Hepatocellular/radiotherapy , Ablation Techniques/methods , Radiotherapy, Image-Guided/methods , Liver Neoplasms/radiotherapy , Radiation Dosage , Iridium Radioisotopes , Tomography, X-Ray Computed , Treatment Outcome , Carcinoma, Hepatocellular/diagnostic imaging , Liver Neoplasms/diagnostic imagingABSTRACT
Background: Squamous Cell Carcinoma (SCC) of the lip represents about 20% of all oral carcinomas. It is more common in men, peaking during their sixth and seventh decade, and is more prevalent in the lower lip. Aim: To determine the five years survival rate of Chilean patients with lip SCC. Material and Methods: The registry of the Chilean National Cancer Institute was reviewed to retrieve the clinical records of patients with lip SCC. Information about age, sex, alcohol consumption, smoking, degree of pathological differentiation, lip location, type of treatment and metastases was recorded. Survival was determined with death certificates from the National Identification Service. Results: Seventy four patients were identified. Their 5-year survival was 73%. Conclusions: The survival rate of this group of patients is lower than that of patients from Unites States who have an 89.5% survival, according to the Surveillance, Epidemiology, and End Results Program of the North American National Cancer Institute.
Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Carcinoma, Squamous Cell/mortality , Lip Neoplasms/mortality , Chile/epidemiology , Prevalence , Risk Factors , Survival Analysis , Survival Rate , Time FactorsABSTRACT
OBJETIVO: Analizar la dosimetría en braquiterapia ginecólogica para el dispositivo Fletcher-Suit-Delclos con alta tasa de dosis, mediante placas radiográficas ortogonales (anteroposterior y lateral) versus tomografía axial computada (TAC). MATERIAL Y MÉTODOS: Se compararon dosimetrías de 4 implantes, realizadas con placas ortogonales y TAC pélvico en la Unidad de Braquiterapia del Instituto Nacional del Cáncer durante el mes de febrero del año 2006. Se prescribieron dosis de 8 Gy/fracción a punto H y se evaluó dosis a vejiga, recto y vagina según norma internacional. RESULTADOS: Las dosimetrías por TAC mostraron puntos calientes superiores a las placas ortogonales, para recto un 133% y para vejiga un 260% más aproximadamente. El porcentaje de volumen blanco incluido es subestimado con la dosimetría efectuada por placas ortogonales. CONCLUSIONES: La dosimetría por placas ortogonales muestra menor exactitud que el TAC. Los volúmenes blanco no son satisfactoriamente cubiertos por la curva de isodosis prescrita. La dosis acumulada, probablemente, sea más relevante que la dosis fracción.
OBJECTIVE: We analyze the gynecologycal high dose rate brachytherapy dosimetry using the Fletcher-Suit-Delclos device, comparing orthogonal films (anteroposterior and lateral) versus axial computarized tomography. METHODS: 4 implants were analized with orthogonal films and axial computarized tomography in the Brachyhterapy Unit of the National Cancer Institute on February 2006. The dose/fraction was 8 Gy to the H point. The bladder, rectal and vaginal dose point were evaluated according to international specifications. RESULTS: Axial computarized tomography reveals hot points higher than orthogonal films dosimetries (133% and 260% for bladder and rectum respectively). The target volumen included was underestimated with the classical orthogonal film dosimetry. CONCLUSIONS: The orthogonal film dosimetry shows smaller accuracy than axial computarized tomography. The target volumens were not satisfactorily covered by the prescribed isodosis curve. The dose accumulated could, probably, be more prominent than the dose/fraction.